Gandhi J, Gugliucci C L
J Reprod Med. 1982 Feb;27(2):80-8.
Eighty-six patients were selected from the high-risk group delivered at Lincoln Hospital in New York City, constituting 22% of the total of 3,500 patients delivered. All of them underwent a nonstress test (NST) and oxytocin challenge test (OCT) antepartally and were also monitored during labor. Sixty-six of them had reactive nonstress patterns, all associated with a negative OCT. Three of them who had reduced variability developed late decelerations in labor; only one had a low Apgar score. Nineteen patients had absence of unequivocal accelerations, five associated with a negative OCT. Of these, only one developed late decelerations in labor. Of 14 others with nonreactive or combined positive OCT patterns, 9 developed late decelerations in labor. Two of them who also had reduced variability developed severe late decelerations in early labor, were delivered by cesarean section and had severe perinatal asphyxia. One case of baseline bradycardia was observed, and the patient did well. When reactive, NST appears to be as reliable as a negative OCT as an indicator of antepartum fetal well-being. Labor may be a life-threatening stress for fetuses displaying nonreactive positive OCT patterns with diminished variability.
86例高危患者选自纽约市林肯医院分娩的产妇,占3500例分娩产妇总数的22%。所有患者产前均接受了无应激试验(NST)和缩宫素激惹试验(OCT),分娩期间也进行了监测。其中66例无应激试验结果呈反应型,均与OCT阴性相关。其中3例变异度降低的患者在分娩时出现晚期减速;只有1例阿氏评分低。19例患者无明确的加速反应,5例与OCT阴性相关。其中,只有1例在分娩时出现晚期减速。在其他14例无反应型或OCT联合阳性型患者中,9例在分娩时出现晚期减速。其中2例变异度也降低的患者在分娩早期出现严重晚期减速,通过剖宫产分娩,并有严重的围产期窒息。观察到1例基线心动过缓病例,患者情况良好。当结果呈反应型时,NST作为产前胎儿健康指标似乎与OCT阴性一样可靠。对于表现为无反应型阳性OCT模式且变异度降低的胎儿,分娩可能是一种危及生命的应激。