Bernad P G, Silber B, Mathieu A
Anesth Analg (Paris). 1980;37(7-8):427-8.
Enflurane has been implicated with both hepatic and renal toxicity. Others factors associated with similar dysfunction in the post operative period should be ruled out before the drug can be incriminated. We are reporting a case of mild post operative jaundice and transient renal insufficiency associated with enflurane anesthesia, which was eventually treated vigorously and successfully. The exact frequency of this kind of post operative complication is still unknown. Although other types of viral hepatitis cannot be completely ruled out, the anesthesiologist should be aware of the potential hazard of hepatic and renal toxicity attributed to enflurane. He should also be prepared to initiate vigorous treatment of the syndrome as soon as it appears so as to increase the chance for a successful outcome.
安氟醚已被认为与肝毒性和肾毒性有关。在确定该药物有罪之前，应排除术后出现类似功能障碍的其他因素。我们报告一例与安氟醚麻醉相关的轻度术后黄疸和短暂性肾功能不全病例，该病例最终经过积极治疗并成功治愈。这种术后并发症的确切发生率仍然未知。虽然不能完全排除其他类型的病毒性肝炎，但麻醉医生应意识到安氟醚所致肝毒性和肾毒性的潜在危害。他还应准备好在该综合征一旦出现时就立即开始积极治疗，以增加成功治愈的机会。
