• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

The synthesis and antitumor activity of arabinosyl-5-azacytosine.

作者信息

Beisler J A, Abbasi M M, Driscoll J S

出版信息

Biochem Pharmacol. 1977 Dec 15;26(24):2469-72. doi: 10.1016/0006-2952(77)90463-4.

DOI:10.1016/0006-2952(77)90463-4
PMID:74254
Abstract
摘要

相似文献

1
The synthesis and antitumor activity of arabinosyl-5-azacytosine.阿拉伯糖基-5-氮杂胞嘧啶的合成及其抗肿瘤活性
Biochem Pharmacol. 1977 Dec 15;26(24):2469-72. doi: 10.1016/0006-2952(77)90463-4.
2
Synthesis and antitumor activity of 5-azacytosine arabinoside.5-氮杂胞嘧啶阿拉伯糖苷的合成与抗肿瘤活性
J Med Chem. 1979 Oct;22(10):1230-4. doi: 10.1021/jm00196a015.
3
Synthesis and antitumor activity of dihydro-5-azacytidine, a hydrolytically stable analogue of 5-azacytidine.二氢-5-氮杂胞苷（5-氮杂胞苷的一种水解稳定类似物）的合成与抗肿瘤活性
J Med Chem. 1977 Jun;20(6):806-12. doi: 10.1021/jm00216a013.
4
Mechanism of action of 1-beta-D-arabinofuranosyl-5-azacytosine and its effects in L1210 mouse leukemia cells.
Neoplasma. 1986;33(1):3-10.
5
Comparison of the activity of arabinosyl-5-azacytosine, arabinosyl cytosine, and 5-azacytidine against intracerebrally implanted L1210 leukemia.
Invest New Drugs. 1985;3(4):331-4. doi: 10.1007/BF00170754.
6
Novel arabinofuranosyl derivatives of cytosine resistant to enzymatic deamination and possessing potent antitumor activity.对酶促脱氨具有抗性且具有强大抗肿瘤活性的新型胞嘧啶阿拉伯呋喃糖基衍生物。
J Med Chem. 1978 Jul;21(7):597-8. doi: 10.1021/jm00205a001.
7
Pyrimidine nucleosides. 6. Syntheses and anticancer activities of N4-substituted 2,2'-anhydronucleosides.嘧啶核苷。6. N4-取代的2,2'-脱水核苷的合成及抗癌活性。
J Med Chem. 1974 Oct;17(10):1076-8. doi: 10.1021/jm00256a010.
8
Arabinosyl-5-azacytosine: plasma kinetics and therapeutic response (L1210) in vitro and in vivo in mice.
Invest New Drugs. 1985;3(4):323-9. doi: 10.1007/BF00170753.
9
Synthesis and anti-cancer activity of some novel 5-azacytosine nucleosides.一些新型5-氮杂胞嘧啶核苷的合成及其抗癌活性
Nucleosides Nucleotides Nucleic Acids. 2003 Dec;22(12):2161-70. doi: 10.1081/ncn-120026872.
10
Nucleic acids. 11. Synthesis of 5'-esters of 1-beta-D-arabinofuranosylcytosine possessing antileukemic and immunosuppressive activity.核酸。11. 具有抗白血病和免疫抑制活性的1-β-D-阿拉伯呋喃糖基胞嘧啶5'-酯的合成。
J Med Chem. 1971 Dec;14(12):1159-62. doi: 10.1021/jm00294a004.

引用本文的文献

1
Phase II study of fazarabine (NSC 281272) in patients with metastatic colon cancer.
Invest New Drugs. 1993 Feb;11(1):71-4. doi: 10.1007/BF00873915.
2
Arabinofuranosyl-5-azacytosine: activity against human tumors in athymic mice.
Cancer Chemother Pharmacol. 1989;25(2):117-23. doi: 10.1007/BF00692351.
3
Arabinosyl-5-azacytosine: a novel nucleoside entering clinical trials.
Invest New Drugs. 1987 Dec;5(4):315-28. doi: 10.1007/BF00169970.
4
Comparison of the activity of arabinosyl-5-azacytosine, arabinosyl cytosine, and 5-azacytidine against intracerebrally implanted L1210 leukemia.
Invest New Drugs. 1985;3(4):331-4. doi: 10.1007/BF00170754.
5
Phase II trial of fazarabine (arabinofuranosyl-5-azacytidine) in patients with advanced pancreatic adenocarcinoma.法扎拉滨（阿糖呋喃基-5-氮杂胞苷）用于晚期胰腺腺癌患者的II期试验。
Invest New Drugs. 1992 Aug;10(3):205-9. doi: 10.1007/BF00877247.
6
Phase I trial of a 72-h continuous-infusion schedule of fazarabine.
Cancer Chemother Pharmacol. 1992;30(4):321-4. doi: 10.1007/BF00686303.
7
Phase II trial of fazarabine (ARA-AC, arabinosyl-5-azacytosine) in metastatic breast cancer.
Invest New Drugs. 1992 Apr;10(1):43-4. doi: 10.1007/BF01275480.