Godeau P, Bletry O, Garin J L, Amiel J L, Lambolez T, Brochard C, Beaulieu J L
Ann Med Interne (Paris). 1980;131(4):223-7.
The first case of placental choriocarcinoma producing clinical hyperthyroidism reported in France is described. Recovery occurred, with disappearance of the choriocarcinoma metastases and hyperthyroidism signs, after chemotherapy alone (vincristine and methotrexate). A review of the seven cases reported in the published literature showed that the hyperthyroidism could be related to the thyroid-stimulating activity of the tumoral gonadotropin (HCG).