Martini N, Melamed M R
Ann Thorac Surg. 1980 Sep;30(3):215-23. doi: 10.1016/s0003-4975(10)61248-9.
In 1974, we reported 26 patients with roentgenographically occult lung carcinomas. In 13 (50%) of them, the tumor was localized and treated by resection while the disease was still early (Stage I). These patients have done well, and the median survival has reached 8 years. We have added 21 patients to the series since our last report. Localization was by fiberoptic bronchoscopy in all 21. Fourteen of these patients had Stage I disease and were treated by resection. Of a total of 27 patients with early disease treated by resection, none has had recurrence after follow-up extending from 2 months to 20 years. However, in 21 of the entire 47 patients (45%) a second carcinoma developed, 15 (71%) of which were second lung carcinomas.
1974年,我们报告了26例X线隐匿性肺癌患者。其中13例(50%)肿瘤局限,在疾病仍处于早期(I期)时接受了切除治疗。这些患者情况良好,中位生存期已达8年。自上次报告以来,我们在该系列中又增加了21例患者。所有21例均通过纤维支气管镜进行定位。其中14例患者为I期疾病,接受了切除治疗。在总共27例接受切除治疗的早期疾病患者中,随访2个月至20年,无一例复发。然而,在全部47例患者中的21例(45%)发生了第二种癌症,其中15例(71%)为第二种肺癌。