Sanchez M A, Font R G
Am J Gastroenterol. 1978 Nov;70(5):496-500.
Review of the literature finds a strong point made for polyps of the stomach to be considered as "sentinels" of malignancy. The controversy over the transformation of gastric polyps into malignant tumors is coming to an end. Apparently, everyone agrees with a high incidence of malignant transformation in adenomatous polyps. The recent case report by Papp and Joseph of a hyperplastic polyp with malignant changes, seems to demonstrate that all polyps can undergo neoplastic transformation. We believe that every gastrectomized patient should be gastroscoped once a year, even with an absence of symptoms or lack of x-ray findings. Any polyp, adenomatous or hyperplastic, should be removed endoscopically and studied histopathologically for possible association with or development of carcinoma.
文献综述发现,有充分的理由将胃息肉视为恶性肿瘤的“哨兵”。关于胃息肉转变为恶性肿瘤的争议即将结束。显然,每个人都认同腺瘤性息肉的恶性转变发生率很高。帕普和约瑟夫最近报告的一例发生恶性变化的增生性息肉病例,似乎表明所有息肉都可能发生肿瘤转化。我们认为,每一位接受胃切除手术的患者都应每年接受一次胃镜检查,即使没有症状或X线检查结果异常。任何息肉,无论是腺瘤性还是增生性的,都应通过内镜切除,并进行组织病理学研究,以确定其是否可能与癌症相关或发展为癌症。