Antibodies to heated milk protein in coronary heart disease.

Coronary arteriography was used to identify 37 patients with triple coronary vessel disease and 37 patients with no evidence of occlusive coronary atheroma. Two techniques were used to analyse serum levels of antibodies to heated milk protein, passive haemagglutination and enzyme-linked immunosorbent assay. No significant differences in these antibodies were observed between triple and zero vessel disease patients. Even after applying ECG evidence of myocardial infarction as a further criterion for classifying patients, no evidence was obtained to support the hypothesis that serum antibodies to heated milk protein are elevated in coronary heart disease.