Avogaro P, Bon G B, Cazzolato G, Rorai E
Atherosclerosis. 1980 Sep;37(1):69-76. doi: 10.1016/0021-9150(80)90094-5.
The relationship of VLDL-, LDL-, HDL-cholesterol, VLDL-triglycerides and of apolipoproteins A-I, A-II and apo-D has been studied in 89 survivors of myocardial infarction and in 80 age- and sex-matched controls. The two groups as a whole were analysed as well as sub-groups of subjects divided according to their lipid phenotype (normolipidaemic, IIA, IIB and IV). The data support the view that plasma levels of apo-B and apoA-I as well as their ratio and the TC/apo-B and LDL-C/apo-B ratios are better indicators of lipid derangement in survivors of myocardial infarction than the levels of LDL-cholesterol and HDL-cholesterol. Total cholesterol, total triglycerides, VLDL-cholesterol and VLDL-triglycerides are of no help in discriminating between the two series. The VLDL-C/VLDL-TG ratio in survivors is, however, very close to the ratio thought to be peculiar to type III hyperlipidaemia.
在89名心肌梗死幸存者和80名年龄及性别匹配的对照者中，研究了极低密度脂蛋白（VLDL）胆固醇、低密度脂蛋白（LDL）胆固醇、高密度脂蛋白（HDL）胆固醇、VLDL甘油三酯以及载脂蛋白A-I、A-II和载脂蛋白D之间的关系。对这两组总体进行了分析，同时也对根据脂质表型（正常血脂、IIA型、IIB型和IV型）划分的亚组受试者进行了分析。数据支持这样的观点，即与LDL胆固醇和HDL胆固醇水平相比，载脂蛋白B（apo-B）和载脂蛋白A-I（apoA-I）的血浆水平及其比值以及总胆固醇（TC）/apo-B和低密度脂蛋白胆固醇（LDL-C）/apo-B比值，是心肌梗死幸存者脂质紊乱更好的指标。总胆固醇、总甘油三酯、VLDL胆固醇和VLDL甘油三酯对区分这两个系列没有帮助。然而，幸存者中的VLDL-C/VLDL-TG比值非常接近被认为是III型高脂血症特有的比值。
