Schaer H M, Marx G F
Anaesthesist. 1978 Dec;27(12):553-6.
Acute viral hepatitis is hazardous in the obstetric patient because of associated multi-system involvement which may include coagulation defects. The fetus may be compromised by maternal complications as well as by high levels of indirect bilirubin which crosses the placenta. Cesarean section is frequently indicated for fetal distress or failed progress of labor. An elderly primigravida with severe acute viral hepatitis complicated by gastrointestinal bleeding, hypofibrinogenemia, thrombocytopenia and prolonged prothrombin and partial thromboplastin times required emergency cesarean section. Clotting factors were replenished prior to surgery. General anesthesia with low-dose ketamine induction and high inspired oxygen fraction was considered the method of choice for the specific maternal and fetal problems.
急性病毒性肝炎对产科患者具有危险性,因为它会累及多个系统,可能包括凝血功能缺陷。胎儿可能会因母亲的并发症以及通过胎盘的高水平间接胆红素而受到影响。剖宫产术常用于胎儿窘迫或产程进展不佳的情况。一位患有严重急性病毒性肝炎并伴有胃肠道出血、低纤维蛋白原血症、血小板减少以及凝血酶原时间和部分凝血活酶时间延长的高龄初产妇需要紧急剖宫产。术前补充了凝血因子。考虑到产妇和胎儿的具体问题,选择低剂量氯胺酮诱导和高吸氧分数的全身麻醉作为麻醉方法。