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新生仓鼠眼球摘除术会诱导其视交叉胼胝体连接出现不对称模式。

Neonatal enucleation induces an asymmetric pattern of visual callosal connections in hamsters.

作者信息

Rhoades R W, Dellacroce D D

出版信息

Brain Res. 1980 Nov 24;202(1):189-95.

PMID:7427734
Abstract

Autoradiography and the horseradish peroxidase (HRP) technique were used to investigate visual callosal connections in normal hamsters and in animals which had one eye removed at birth. In normals and in the cortex contralateral to the remaining eye in the neonatal enucleates, callosal cells and terminal labeling were restricted to the region around the area 17-18a border. In the cortex ipsilateral to the remaining eye in the neonatal enucleates labeled cells and terminal labeling were observed throughout areas 17 and 18a.

摘要

利用放射自显影术和辣根过氧化物酶(HRP)技术,研究正常仓鼠以及出生时摘除一只眼睛的动物的视胼胝体连接。在正常仓鼠以及新生摘除眼球动物中与未摘除的眼睛对侧的皮质中,胼胝体细胞和终末标记局限于17区-18a区边界周围区域。在新生摘除眼球动物中与未摘除的眼睛同侧的皮质中,在整个17区和18a区均观察到标记细胞和终末标记。

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