Faradji H, Cespuglio R, Rondot G, Paut L, Jouvet M
Brain Res. 1980 Nov 24;202(1):41-9.
The influence of the light-dark schedule (12 h-12 h) on the sleep-waking cycle has been studied in anophthalmic mice: the 'eyeless' ZRDCT/An strain. The complete anophthalmic mice or the heterozygotous mice of the same strain with unilateral or bilateral eyeballs present a circadian organization of the sleep-waking cycle which is not dependent on the light-dark cycle. These results are different from sleep rhythms of C57Br mice recorded under the same experimental conditions. They indicate that the structures responsible for the circadian rhythmicity of sleep exist in all the 'eyeless' ZRDCT/An mice, but are not functionally linked with the visual system even in the mice with unilateral and bilateral eyeballs.
在无眼小鼠（“无眼”ZRDCT/An品系）中研究了明暗周期（12小时-12小时）对睡眠-觉醒周期的影响。完全无眼的小鼠或同一品系单侧或双侧眼球的杂合子小鼠呈现出睡眠-觉醒周期的昼夜节律组织，该节律不依赖于明暗周期。这些结果与在相同实验条件下记录的C57Br小鼠的睡眠节律不同。它们表明，负责睡眠昼夜节律的结构存在于所有“无眼”ZRDCT/An小鼠中，但即使在单侧和双侧眼球的小鼠中，这些结构在功能上也与视觉系统无关。
