Marcial V A, Hanley J A, Ydrach A, Vallecillo L A
Cancer. 1980 Nov 1;46(9):1910-2. doi: 10.1002/1097-0142(19801101)46:9<1910::aid-cncr2820460903>3.0.co;2-t.
The complications of salvage surgery after radical irradiation were studied in a group of 52 patients with oropharyngeal carcinomas. These patients were selected for surgery from a group of patients who had failed protocol therapy and who were registered in the Split-Course Study of the Radiation Therapy Oncology Group. The operative mortality was 1.9% (1/52). The most frequent serious complication was pharyngocutaneous fistua in 12% (6/52) of patients who underwent operations. The overall incidence of serious complications was 21% (11/52). The actuarial estimated five-year survival for the group who had undergone operation was 27%. We conclude that salvage surgery for residual or recurrent disease in oropharyngeal cancer after radical radiotherapy is feasible with a low surgical mortality and acceptable complication rates.
对一组52例口咽癌患者进行了根治性放疗后挽救性手术并发症的研究。这些患者是从一组未能完成方案治疗且登记在放射治疗肿瘤学组分段疗程研究中的患者中挑选出来进行手术的。手术死亡率为1.9%（1/52）。最常见的严重并发症是12%（6/52）接受手术患者发生的咽皮肤瘘。严重并发症的总发生率为21%（11/52）。接受手术组的精算估计五年生存率为27%。我们得出结论，根治性放疗后口咽癌残留或复发病灶的挽救性手术是可行的，手术死亡率低，并发症发生率可接受。
