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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Auld C D, Light I M, Norman J N

Clin Sci (Lond). 1980 Jun;58(6):501-6. doi: 10.1042/cs0580501.

Hypothermia to a temperature of 30 degrees C was induced in both shivering and non-shivering groups of dogs. 2. There was a sustained increase in oxygen consumption in the dogs allowed to shiver and this was up to 300% greater than the oxygen consumption in the relaxed dogs. 3. The increased tissue requirement for oxygen was met both by increased cardiac output and increased oxygen extraction from haemoglobin. 4. Oxygen utilization remained adequate in hypothermia, as shown by the absence of hypoxic acidosis. 5. Heart rate fell during cooling and stroke volume increased to meet the increased oxygen demands associated with shivering during the induction of hypothermia.

在颤抖和不颤抖的两组狗中均诱导体温降至30摄氏度。2. 允许颤抖的狗的耗氧量持续增加，且比放松状态的狗的耗氧量高出多达300%。3. 心脏输出量增加和从血红蛋白中提取的氧气增加共同满足了组织对氧气增加的需求。4. 低温时氧气利用仍然充足，这表现为无缺氧性酸中毒。5. 在降温过程中，心率下降，每搏输出量增加，以满足低温诱导期间与颤抖相关的增加的氧气需求。

Auld C D, Light I M, Norman J N

Clin Sci (Lond). 1980 Jun;58(6):501-6. doi: 10.1042/cs0580501.

Hypothermia to a temperature of 30 degrees C was induced in both shivering and non-shivering groups of dogs. 2. There was a sustained increase in oxygen consumption in the dogs allowed to shiver and this was up to 300% greater than the oxygen consumption in the relaxed dogs. 3. The increased tissue requirement for oxygen was met both by increased cardiac output and increased oxygen extraction from haemoglobin. 4. Oxygen utilization remained adequate in hypothermia, as shown by the absence of hypoxic acidosis. 5. Heart rate fell during cooling and stroke volume increased to meet the increased oxygen demands associated with shivering during the induction of hypothermia.

在颤抖和不颤抖的两组狗中均诱导体温降至30摄氏度。2. 允许颤抖的狗的耗氧量持续增加，且比放松状态的狗的耗氧量高出多达300%。3. 心脏输出量增加和从血红蛋白中提取的氧气增加共同满足了组织对氧气增加的需求。4. 低温时氧气利用仍然充足，这表现为无缺氧性酸中毒。5. 在降温过程中，心率下降，每搏输出量增加，以满足低温诱导期间与颤抖相关的增加的氧气需求。