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普萘洛尔对家兔性交期间心率、血压及血浆去甲肾上腺素的影响。

Effect of propranolol on heart rate, blood pressure and plasma noradrenaline during coitus in the rabbit.

作者信息

Gordon D, Roddis S A, Sever P S

出版信息

Clin Sci (Lond). 1980 Oct;59(4):231-6. doi: 10.1042/cs0590231.

DOI:10.1042/cs0590231
PMID:7428290
Abstract
  1. The effects of coitus on heart rate, blood pressure and plasma concentration of noradrenaline were studied in six male rabbits. 2. During coitus, heart rate rose from 228 +/- 6 to 324 +/- 8 beats/min (mean +/- SEM; n = 24). Mean blood pressure rose from 87 +/- 3 to 165 +/- 4 mmHg, and plasma concentration of noradrenaline from 2.07 +/- 0.21 to 5.02 +/- 0.26 nmol/l. The maximum heart rate did not occur until after the peak in blood pressure. 3. Propranolol had no effect on the power expended during coitus, but there was a dose dependent fall in the changes in heart rate, blood pressure and plasma concentration of noradrenaline.
摘要
  1. 研究了六只雄性兔子性交对心率、血压和去甲肾上腺素血浆浓度的影响。2. 性交过程中,心率从228±6次/分钟升至324±8次/分钟(平均值±标准误;n = 24)。平均血压从87±3 mmHg升至165±4 mmHg,去甲肾上腺素血浆浓度从2.07±0.21 nmol/L升至5.02±0.26 nmol/L。最大心率直到血压达到峰值后才出现。3. 普萘洛尔对性交过程中消耗的能量没有影响,但对心率、血压和去甲肾上腺素血浆浓度的变化存在剂量依赖性下降。

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1
Effect of propranolol on heart rate, blood pressure and plasma noradrenaline during coitus in the rabbit.普萘洛尔对家兔性交期间心率、血压及血浆去甲肾上腺素的影响。
Clin Sci (Lond). 1980 Oct;59(4):231-6. doi: 10.1042/cs0590231.
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The effect of captopril and propranolol on the responses to posture and isometric exercise in patients with essential hypertension.卡托普利和普萘洛尔对原发性高血压患者姿势及等长运动反应的影响。
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Time course of blood pressure changes after intravenous administration of propranolol or furosemide in hypertensive patients.高血压患者静脉注射普萘洛尔或呋塞米后血压变化的时间进程。
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Blood pressure and norepinephrine spillover during propranolol infusion in humans.普萘洛尔输注期间人体的血压和去甲肾上腺素外溢情况。
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Propranolol and atenolol inhibit norepinephrine spillover rate into plasma in conscious spontaneously hypertensive rats.普萘洛尔和阿替洛尔可抑制清醒自发性高血压大鼠血浆中去甲肾上腺素的溢出率。
Naunyn Schmiedebergs Arch Pharmacol. 1991 Jul;344(1):47-55. doi: 10.1007/BF00167382.

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Studies on the renin response to vasoactive intestinal polypeptide (VIP) in the conscious rabbit.清醒家兔中肾素对血管活性肠肽(VIP)反应的研究。
Br J Pharmacol. 1983 Sep;80(1):13-5. doi: 10.1111/j.1476-5381.1983.tb11043.x.
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Coital blood pressure in hypertensives. Cephalgia, syncope, and the effects of beta-blockade.高血压患者的性交时血压。头痛、晕厥以及β受体阻滞剂的作用。
Br Heart J. 1982 Jan;47(1):84-9. doi: 10.1136/hrt.47.1.84.