Iwata M, Hirano A
Ann Neurol. 1978 Dec;4(6):562-3. doi: 10.1002/ana.410040617.
"Glial bundles" in the proximal portion of the anterior spinal roots, identical to those in Werdnig-Hoffmann disease, were observed in 3 patients many years after attacks of acute paralytic anterior poliomyelitis. These structures should therefore be considered a nonspecific astrocytic reaction secondary to the destruction of motor neurons and their axons rather than a malformation specific for Werdnig-Hoffman disease.
在3例急性麻痹性脊髓灰质炎发作多年后的患者中,观察到脊髓前根近端存在“胶质束”,与韦尼克 - 霍夫曼病中的情况相同。因此,这些结构应被视为运动神经元及其轴突破坏后的非特异性星形细胞反应,而非韦尼克 - 霍夫曼病特有的畸形。