Doetschman T C, Dym H P, Siegel E J, Heywood S M
Differentiation. 1980 Jun;16(3):149-62. doi: 10.1111/j.1432-0436.1980.tb01071.x.
Radioactively labeled myosin heavy chain messenger ribonucleic acid (MHC mRNA) synthesized during the pre-fusion stage of chick embryo breast muscle cell culture is transferred from messenger ribonucleic acid proteins (mRNPs) to the polysomal MHC mRNA during the period of rapid increase in the rate of MHC synthesis (mid-to late-fusion). This transfer constitutes a major contribution to the rate of incorporation of 3H-labeled transcripts into polysomal MHC mRNA at this time. As the increase in the rate of MHC synthesis levels off (late-to post-fusion) the contribution to the rate of incorporation of 3H-labeled transcripts into polysomal MHC mRNA from newly synthesized transcripts increases until it becomes predominant. In vivo, the level of MHC mRNP increases during early stages of embryonic development and then decreases when MHC synthesis and the level of polysomal MHC mRNA has been shown to increase.
在鸡胚胸肌细胞培养的预融合阶段合成的放射性标记肌球蛋白重链信使核糖核酸（MHC mRNA），在MHC合成速率快速增加的时期（融合中期至后期）从信使核糖核酸蛋白（mRNP）转移至多聚核糖体MHC mRNA。此时，这种转移对3H标记转录本掺入多聚核糖体MHC mRNA的速率有主要贡献。随着MHC合成速率的增加趋于平稳（融合后期至融合后），新合成转录本对3H标记转录本掺入多聚核糖体MHC mRNA速率的贡献增加，直至占主导地位。在体内，MHC mRNP水平在胚胎发育早期升高，然后在MHC合成增加且多聚核糖体MHC mRNA水平已被证明升高时下降。
