Eckardt V F, Adami B, Hücker H, Leeder H
Gastroenterology. 1980 Sep;79(3):426-30.
This study investigates whether asymptomatic lower esophageal mucosal rings are associated with a hiatus hernia or whether they represent an upward migration of columnar epithelium into the esophagus. Simultaneous manometric and potential difference measurements were performed in 12 patients with radiologically documented lower esophageal rings and in 15 control subjects. Suction biopsies from the lower esophagus confirmed that the potential difference transitional zone identified the mucosal gastroesophageal junction. In both patients and controls the esophagogastric mucosal junction was identified within or below the lower esophageal sphincter. It is concluded that the lower esophageal mucosal ring marks the lower end of the esophagus and does not represent a dislocation of the esophagogastric mucosal junction away from the lower esophageal sphincter.
本研究旨在调查无症状的食管下黏膜环是否与食管裂孔疝相关，或者它们是否代表柱状上皮向食管的向上迁移。对12例经放射学证实有食管下环的患者和15例对照者同时进行了测压和电位差测量。来自食管下段的吸引活检证实，电位差过渡区确定了黏膜胃食管交界。在患者和对照者中，食管胃黏膜交界均位于食管下括约肌内或其下方。结论是，食管下黏膜环标志着食管的下端，并不代表食管胃黏膜交界从食管下括约肌处移位。
