XX（BALB）/XY（C3H）嵌合雄性小鼠睾丸中的H-Y抗原。

H-Y antigen in testes of XX(BALB)/XY (C3H) chimaeric male mouse.

作者信息

Ohno S, Ciccarese S, Nagai Y, Wachtel S S

出版信息

Arch Androl. 1978;1(1):103-9. doi: 10.3109/01485017808988325.

Abstract

Among experimentally produced BALB/C3H aggregation (Blastocyst fusion) chimaeras of the mouse, one fertile XX (BALB)/XY (C3H) male was identified who maintained 50% or more female cells in many parts of his body. Results of H-Y antibody absorption tests revealed an XY to XX transfer of testis-organizing H-Y antigen among testicular Sertoli and Leydig cells, but not among spleen and epidermal cells.

摘要

在实验产生的小鼠BALB/C3H聚合（囊胚融合）嵌合体中，鉴定出一只可育的XX（BALB）/XY（C3H）雄性，其身体许多部位维持着50%或更多的雌性细胞。H-Y抗体吸收试验结果显示，睾丸组织的H-Y抗原在睾丸支持细胞和间质细胞之间从XY向XX转移，但在脾细胞和表皮细胞之间未发生转移。