Pietrzik K, Urban G, Hötzel D
Int J Vitam Nutr Res. 1980;50(3):261-6.
In a study on 250 industrial workers the amount of the formiminoglutamic acid excretion in urine was measured by an enzymatic spectrophotometric method. For the estimation of the folacine status the vitamine concentration in serum and erythrozytes was determined as well as the segmentation of the neutrophilic granulocytes. As shown in previous studies these parameters indicate the degree of folate supply. A correlation between the FIGLU excretion in urine and other folate dependent parameters could not be demonstrated. Criterial to judge the folate supply are the radioimmunological determination of folacine concentration in serum and erythrocytes as well as the estimation of the segmentation of the neutrophilic granulocytes.
在一项针对250名产业工人的研究中，采用酶分光光度法测定了尿中亚胺甲基谷氨酸的排泄量。为评估叶酸状态，还测定了血清和红细胞中的维生素浓度以及中性粒细胞的核分叶情况。如先前研究所示，这些参数表明了叶酸供应程度。尿中亚胺甲基谷氨酸排泄量与其他叶酸依赖参数之间未显示出相关性。判断叶酸供应的标准是血清和红细胞中叶酸浓度的放射免疫测定以及中性粒细胞核分叶情况的评估。
