Kistner T P, Wyse D
Aust Vet J. 1978 Oct;54(10):469-70. doi: 10.1111/j.1751-0813.1978.tb00287.x.
Eighteen parasite-free sheep were each infected with 6000 +/- 25 infective larvae of the AH-2, benzimidazole-resistant strain of Haemonchus contortus on each of experimental days -27, -15, -8 and -1. The sheep were subsequently randomized into 3 groups of 6 sheep each. Group 1 served as untreated controls; Groups 2 and 3 were treated orally with oxfendazole at dose levels of 5 mg/kg and 10 mg/kg body weight, respectively. At both dosage levels, oxfendazole was 100% effective against third, fourth, early fifth, and adult stages of the worms.
在实验第-27、-15、-8和-1天，18只无寄生虫的绵羊每只分别感染6000±25条捻转血矛线虫AH-2苯并咪唑抗性株的感染性幼虫。随后将绵羊随机分为3组，每组6只。第1组作为未治疗的对照组；第2组和第3组分别以5mg/kg和10mg/kg体重的剂量口服奥芬达唑。在这两个剂量水平下，奥芬达唑对该蠕虫的第三、第四、早期第五和成虫阶段均有100%的疗效。
