Raczkowski D, Diamond I T
J Comp Neurol. 1980 Sep 1;193(1):1-40. doi: 10.1002/cne.901930102.
In the first series of experiments, small amounts of HRP were injected into areas 17, 18, and 19 and each of the cytoarchitectonic areas of the temporal lobe. The resulting distributions of labeled cells fell into a number of distinctive classes. For example, after injecting the temporal anterior area (Ta), the labeled cells occupied a band on the ventral border of the inferior division of the pulvinar complex; after injecting the temporal ventral area (Tv), the labeled cells were concentrated in the medial extremity of the superior division. In spite of the distinctiveness of these different distributions, there was evidence that in areas that we know to contain a representation of the visual field, the injection of the same part of the field led to labeled cells in the same part of the pulvinar nucleus. Thus, when the representation of the center of the field was injected in areas 17 or 18 or Tm (the temporal middle area), labeled cells were found in the dorsal part of the rostral half of the inferior division. The distinctiveness of the different distributions did not obscure certain features common to all experiments: labeled cells were always found in both subdivisions of the pulvinar complex, and there was always continuity between the population of labeled cells in the inferior division and the population of cells in the superior division. Wherever the site of the injection in the extrastriate region, some labeled cells were found in the causal half of the inferior division. Since the caudal half of the inferior division corresponds approximately to the tecto-recipient zone as defined earlier, the entire temporal lobe, except for the auditory areas, is visual cortex. Evidence was also found for an overlap in the striate cortex between the projections of the lateral geniculate body and the pulvinar nucleus. In conclusion, the pulvinar complex projects to a vast area of cortex, including all of the occipital lobe and most of the lateral surface of the temporal lobe. This entire region, which comprises a good part of the whole of the neocortex, can be regarded as visual cortex. A second series of experiments involved cortical injections of tritiated amino acids. The results showed that the projections from the thalamus to cortex were precisely reciprocated by descending projections from cortex to thalamus. The results also served as a way of confirming the results of the first set of experiments.
在第一系列实验中，将少量辣根过氧化物酶（HRP）注入17区、18区、19区以及颞叶的各个细胞构筑区。标记细胞的最终分布可分为若干不同类别。例如，在注入颞前区（Ta）后，标记细胞占据了丘脑枕复合体下部分腹侧边界的一条带；在注入颞腹区（Tv）后，标记细胞集中在上部分的内侧末端。尽管这些不同分布具有独特性，但有证据表明，在我们已知包含视野表征的区域，注入视野的同一部分会导致丘脑枕核同一部分出现标记细胞。因此，当在17区、18区或颞中区（Tm）注入视野中心的表征时，在下部分喙侧半的背侧部分发现了标记细胞。不同分布的独特性并未掩盖所有实验共有的某些特征：在丘脑枕复合体的两个亚区都总能发现标记细胞，并且下部分的标记细胞群体与上部分的细胞群体之间始终存在连续性。无论在纹外区的注射部位在哪里，在下部分的因果半区都能发现一些标记细胞。由于下部分的尾侧半区大致对应于先前定义的顶盖接受区，所以除听觉区外，整个颞叶都是视皮层。还发现了外侧膝状体和丘脑枕核的投射在纹状皮层中有重叠的证据。总之，丘脑枕复合体投射到广泛的皮层区域，包括整个枕叶和颞叶外侧表面的大部分。这个整个区域，构成了整个新皮层的很大一部分，可以被视为视皮层。第二系列实验涉及向皮层注射氚标记的氨基酸。结果表明，从丘脑到皮层的投射被从皮层到丘脑的下行投射精确地反向对应。这些结果也作为一种确认第一组实验结果的方式。
