Giovinazzo V J, Harber L C, Armstrong R B, Kochevar I E
J Am Acad Dermatol. 1980 Oct;3(4):384-93.
Two male patients with photoallergic contact dermatitis to musk ambrette, 2-methoxy-3,5-dinitro-4-methyl-t-butylbenzene, are reported. Musk ambrette is a synthetic fragrance material commonly used in foods and cosmetics. The clinical distribution of lesions presented by these patients strongly suggested an adverse reaction to light. Over a period of several years no etiology had been determined in these cases despite extensive testing and hospitalization. Photopatch tests to musk ambrette were positive. No other etiology for photosensitivity was found. This report emphasizes that exposure to household or cosmetic products represents a potential source of contact photosensitivity. Patients presenting with dermatoses of unknown origin confined to the light-exposed areas should have fragrances considered as possible etiologic agents.
报告了2例对葵子麝香（2-甲氧基-3,5-二硝基-4-甲基叔丁基苯）发生光变应性接触性皮炎的男性患者。葵子麝香是一种常用于食品和化妆品的合成香料。这些患者皮损的临床分布强烈提示对光的不良反应。尽管经过广泛检查和住院治疗，数年来这些病例的病因一直未明确。对葵子麝香的光斑贴试验呈阳性。未发现其他光敏病因。本报告强调，接触家用产品或化妆品是接触性光敏反应的一个潜在来源。表现为局限于暴露部位的不明原因皮肤病患者应考虑香料可能为致病因素。
