Ghosh P
J Laryngol Otol. 1980 Jul;94(7):719-35. doi: 10.1017/s0022215100089489.
A new diagnostic parameter in electro-oculography, viz. 'Inclination of eye-tracking tracing' is presented. Electro-oculographically the pendular eye-tracking tracing was recorded before and after calorization, using the technique of serial thermal vestibulometry. In some cases of brain-stem lesion, the tracing inclined in the direction of the slow component of the calorically-induced nystagmus; but this phenomenon was not noted in cases with peripheral lesions, nor in pure frontal, occipital, parietal of cerebellar lesions. A neuro-anatomical model is postulated in explanation of this phenomenon. It appears that the basic lesion responsible for this phenomenon is a small one partially involving the slow-discharging neuronal units in the lower reticular core and in the adjacent suprasegmental inhibitory cortico-reticular tracts, thus bringing about a state of relative hyperactivity (release phenomenon) of the remaining surviving neurones which belong to the slow-discharging neuronal units. The latter has been referred to here as the 'Inclination Neuronal Mechanism' and this phenomenon appears to be the converse of "Central vestibular recruitment', the former being caused by a lesion in the 'slow-discharging units', the latter by a lesion in the 'quick-discharging units' ('nystagmogenic area'), the two units belonging to the same reticular system but having opposite functions.
本文介绍了眼电图中的一种新诊断参数，即“眼动轨迹倾斜度”。采用系列热前庭功能测定技术，在冷热试验前后用眼电图记录摆动性眼动轨迹。在一些脑干病变病例中，眼动轨迹向冷热诱发眼震慢相方向倾斜；但在外周病变病例以及单纯额叶、枕叶、顶叶或小脑病变病例中未观察到这种现象。为解释这一现象，提出了一个神经解剖学模型。看来导致这种现象的基本病变是一个小病变，部分累及低位网状核和相邻的节段上抑制性皮质网状束中的慢放电神经元单元，从而使属于慢放电神经元单元的其余存活神经元处于相对活动亢进状态（释放现象）。后者在此被称为“倾斜神经元机制”，这种现象似乎与“中枢前庭募集”相反，前者由“慢放电单元”病变引起，后者由“快放电单元”（“眼震发生区”）病变引起，这两个单元属于同一网状系统但功能相反。
