Abildskov J A
J Electrocardiol. 1980 Oct;13(4):307-10. doi: 10.1016/s0022-0736(80)80080-x.
Effects of localized destructive myocardial lesions on the QRS complex of vectorcardiographic leads was studied by graphic derivation of vectors from the detailed activation sequence of the human heart. Lesions of three sizes were postulated at each of 16 cardiac locations and differences between derived vectors in the presence and absence of lesions determined. At each location there was a near linear relation between lesion size and vector differences. Over different locations, however, there were marked variations in the effects of lesions of a particular size. Variations were due to varied activation patterns within each left ventricular wall since the contribution of each wall (anterior, lateral, posterior and septal) to QRS waveform was nearly identical. Findings suggest that the size of extensive destructive lesions will be well represented by the degree of QRS complex change in vectorcardiographic leads but that vectocardiographic estimates of the size of small lesions or of change of size of either small or large lesions are subject to substantial error.
通过从人体心脏详细的激动顺序进行向量的图形推导，研究了局限性心肌破坏性病变对心电向量图导联QRS波群的影响。在16个心脏部位的每一个部位设定三种大小的病变，并确定存在和不存在病变时推导向量之间的差异。在每个部位，病变大小与向量差异之间存在近似线性关系。然而，在不同部位，特定大小病变的影响存在显著差异。这些差异是由于每个左心室壁内不同的激动模式所致，因为每个壁（前壁、侧壁、后壁和间隔）对QRS波形的贡献几乎相同。研究结果表明，广泛破坏性病变的大小将通过心电向量图导联中QRS波群变化的程度得到很好的体现，但心电向量图对小病变大小或小病变或大病变大小变化的估计存在很大误差。
