大鼠肝脏中AIB转运的每日节律与调节
Daily rhythm and regulation of AIB transport in rat liver.
作者信息
Ehrhardt V
出版信息
Chronobiologia. 1977 Jul-Sep;4(3):205-13.
The active transport of AIB in rat liver slices shows a daily rhythm with a maximum at 18(00) and a minimum at 10(00). The rhythmic increase of transport activity is inhibited by cycloheximide. At the time of low transport rate, cycloheximide does not affect AIB transport. During the diurnal decrease of AIB transport activity, after its maximum, cycloheximide partially diminishes the transport rate. 5-azacytidine and alpha-amanitin stimulate AIB transport. The stimulation is prevented by simultaneous administration of cycloheximide.
大鼠肝切片中AIB的主动转运呈现出日节律，在18:00达到最大值，在10:00达到最小值。转运活性的节律性增加受到环己酰亚胺的抑制。在转运速率较低时，环己酰亚胺不影响AIB的转运。在AIB转运活性达到最大值后出现的昼夜下降过程中，环己酰亚胺会部分降低转运速率。5-氮杂胞苷和α-鹅膏蕈碱刺激AIB的转运。同时给予环己酰亚胺可阻止这种刺激作用。
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