Grey J E, Lauf P K
Membr Biochem. 1980;3(1-2):21-35. doi: 10.3109/09687688009063876.
The effect of cholesterol depletion on potassium tracer fluxes was studied in sheep red cells. Removal by the plasma incubation method (5, 12, 30) of approximately 31 and 34% membrane cholesterol from high-potassium (HK) and low-potassium (LK) sheep red cells, respectively, did not induce significant changes in the steady-state cation composition of these cells nor in their passive (leak) and active (pump) K+ influxes. In cholesterol-depleted LK sheep red cells, there was no impairment nor augmentation of the Lp an antibody stimulated K+ pump flux and L1-antibody-mediated reduction of K+ leak flux indicating that the removed cholesterol does not contribute to the activity of the Lp and L1 antigens.
在绵羊红细胞中研究了胆固醇耗竭对钾示踪剂通量的影响。通过血浆孵育法（5、12、30）分别从高钾（HK）和低钾（LK）绵羊红细胞中去除约31%和34%的膜胆固醇，这些细胞的稳态阳离子组成及其被动（渗漏）和主动（泵）钾离子内流均未发生显著变化。在胆固醇耗竭的LK绵羊红细胞中，Lp抗体刺激的钾离子泵通量和L1抗体介导的钾离子渗漏通量降低均未受损或增强，这表明去除的胆固醇对Lp和L1抗原的活性没有贡献。
