Comper W D, Laurent T C
Biochem J. 1978 Nov 1;175(2):703-8. doi: 10.1042/bj1750703.
It is demonstrated that exclusion phenomena appear to dominate the interaction of dextran with albumin in aqueous solution. The enthalpic contribution to the interaction coefficient describing dextran/albumin mixtures is small, although its determination was subject to considerable error. These results support the earlier assumptions of the type of interaction between the two polymers. The conclusions are primarily based on the interpretation of the temperature-dependence of the interaction coefficient, as measured by light-scattering in the temperature range 6--33 degrees C. Enthalpy of dilution measurements of dextran/albumin mixtures by microcalorimetry were in qualitative agreement with the light-scattering data.
结果表明，在水溶液中，排斥现象似乎主导了葡聚糖与白蛋白的相互作用。尽管对描述葡聚糖/白蛋白混合物的相互作用系数的焓贡献的测定存在相当大的误差，但其数值较小。这些结果支持了之前关于这两种聚合物相互作用类型的假设。这些结论主要基于对相互作用系数的温度依赖性的解释，该系数是通过在6 - 33摄氏度温度范围内的光散射测量得到的。通过微量量热法对葡聚糖/白蛋白混合物进行的稀释焓测量与光散射数据在定性上是一致的。
