Bobrow M, Heritage J
Nature. 1980 Nov 6;288(5786):79-81. doi: 10.1038/288079a0.
The random assortment of non-homologous chromosomes at meiosis is one of the fundamental tenets of genetics, to which few exceptions have been documented. The segregation of mitotic chromatids is believed to be similarly random. We report here that we seem to have discovered a new exception to this rule, in that nucleolar organizing chromosomes remain associated with one another, held in the same lateral orientation, for several mitotic cycles.
减数分裂时非同源染色体的随机分配是遗传学的基本原理之一,鲜有例外记载。有丝分裂染色单体的分离被认为同样是随机的。我们在此报告,我们似乎发现了这一规则的一个新例外,即核仁组织染色体在几个有丝分裂周期中彼此保持关联,以相同的横向方向排列。