Brook I, Friedman E M, Rodriguez W J, Controni G
Pediatrics. 1980 Oct;66(4):568-72.
Eight patients (6 to 15 years of age) who had periorbital cellulitis and other complications of sinusitis were studied. Both ethmoid and maxillary sinusitis were present in four patients, frontal sinusitis in two, and ethmoid sinusitis and pansinusitis in one patient each. Subdural empyema occurred in four patients, in one case accompanied by cerebritis and brain abscess and in another by meningitis. Periorbital abscess was present in two children who had ethmoiditis. Alveolar abscess in the upper incisors was present in two children whose infection had spread to the maxillary and ethmoid sinuses. Anaerobic bacteria were isolated from the infected sinuses in all the patients. These were seven isolates of Bacteroides sp, four Fusobacterium sp, three microaerophilic streptococci, three Gram-positive anaerobic cocci, and two Veillonella sp. There was only one aerobic isolate recovered, a group F beta-hemolytic. Streptococcus. Surgical drainage and appropriate antimicrobial therapy resulted in complete eradication of the infection in all patients. The role of anaerobic bacteria in sinus infection and its subsequent complication is discussed. Given the possible serious complications of this disease, the early recognition of sinusitis in children and the institution of appropriate antimicrobial and surgical therapy are of great clinical importance.
对8例患有眶周蜂窝织炎及鼻窦炎其他并发症的患者(年龄6至15岁)进行了研究。4例患者同时患有筛窦炎和上颌窦炎,2例患有额窦炎,1例患有筛窦炎,1例患有全鼻窦炎。4例患者发生了硬膜下积脓,1例伴有脑炎和脑脓肿,另1例伴有脑膜炎。2例患有筛窦炎儿童出现眶周脓肿。2例感染蔓延至上颌窦和筛窦的儿童出现上颌切牙牙槽脓肿。所有患者感染的鼻窦中均分离出厌氧菌。这些厌氧菌包括7株拟杆菌属、4株梭杆菌属、3株微需氧链球菌、3株革兰氏阳性厌氧球菌和2株韦荣球菌属。仅分离出1株需氧菌,为F组β溶血性链球菌。手术引流和适当的抗菌治疗使所有患者的感染完全根除。讨论了厌氧菌在鼻窦感染及其后续并发症中的作用。鉴于该疾病可能出现的严重并发症,儿童鼻窦炎的早期识别以及适当抗菌和手术治疗的实施具有重要的临床意义。