某些邻氨基苯甲酸衍生物的合成及其抗菌活性
Synthesis and antimicrobial activity of some anthranilic acid derivatives.
作者信息
Kar A, Gugnani H C, Madumere U A
出版信息
Pharmazie. 1980 Aug;35(8):466-8. doi: 10.1002/chin.198050227.
PMID:7433494
Abstract
The synthesis of eight derivatives of anthranilic acid is described. Investigation of their antimicrobial activity showed that four of the compounds, viz; anthranilohydrazide, 3,4-dihydro-4-oxo-1,2,3-benzotriazine, triazine-beta-naphthol adduct and N-phenyl anthranilic acid showed significant antibacterial activity. None of the compounds showed any noticeable antifungal effect.
摘要
本文描述了八种邻氨基苯甲酸衍生物的合成。对其抗菌活性的研究表明，其中四种化合物，即邻氨基苯甲酰肼、3,4-二氢-4-氧代-1,2,3-苯并三嗪、三嗪-β-萘酚加合物和N-苯基邻氨基苯甲酸具有显著的抗菌活性。没有一种化合物表现出明显的抗真菌作用。
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