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盐酸美克洛嗪的电导测定法(作者译)

[Conductometric determination of meclozine hydrochloride (author's transl)].

作者信息

Nikolić K I, Popović R B, Vukosavljević M D

出版信息

Pharmazie. 1980 Aug;35(8):479-80.

PMID:7433497
Abstract

The authors describe a conductometric method for determining meclozine hydrochloride as a pure substance and in tablets. The titration is performed with perchloric acid in glacial acetic acid and in ethanolic solution with ethanolic potassium hydroxide solution. As a result, conductometric curves are obtained, the forms of which are suited for the accurate reproducible determination of the end point. The method permits to estimate small amounts of meclozine hydrochloride.

摘要

作者描述了一种用电导法测定盐酸美克洛嗪纯品及其片剂的方法。该滴定是在冰醋酸中用高氯酸进行,在乙醇溶液中用乙醇氢氧化钾溶液进行。结果得到了电导曲线,其形式适合于准确可重复地确定终点。该方法能够测定少量的盐酸美克洛嗪。

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