Nikolić K I, Popović R B, Vukosavljević M D
Pharmazie. 1980 Aug;35(8):479-80.
The authors describe a conductometric method for determining meclozine hydrochloride as a pure substance and in tablets. The titration is performed with perchloric acid in glacial acetic acid and in ethanolic solution with ethanolic potassium hydroxide solution. As a result, conductometric curves are obtained, the forms of which are suited for the accurate reproducible determination of the end point. The method permits to estimate small amounts of meclozine hydrochloride.
作者描述了一种用电导法测定盐酸美克洛嗪纯品及其片剂的方法。该滴定是在冰醋酸中用高氯酸进行,在乙醇溶液中用乙醇氢氧化钾溶液进行。结果得到了电导曲线,其形式适合于准确可重复地确定终点。该方法能够测定少量的盐酸美克洛嗪。