Radiological findings in multiple hamartoma syndrome (Cowden disease): a report of three cases.

The radiological findings in three cases of multiple hamartoma syndrome (MHS) (Cowden disease) are reported. MHS was associated with a widespread distribution of polyps of varied morphology along the gastrointestinal tract. There was an isolated case of bladder carcinoma, and the one woman studied had breast masses. In view of the nonspecific clinical findings in this disease, which may also suggest carcinoma, the importance of the radiological recognition of MHS is stressed.