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低分子量胸腺多肽对豚鼠和小鼠组织及体液水平某些免疫反应的作用

Action of thymic polypeptides of low molecular weight on some immune reactions at tissular and humoral level in guinea-pigs and mice.

作者信息

Milcu S M, Boeru V, Prahoveanu E, Briese M A, Petrescu A, Săvulescu M

出版信息

Endocrinologie. 1980 Jul-Sep;18(3):149-54.

PMID:7433861
Abstract

Administration of the TP2 extract containing thymic polypeptides of low molecular weight (under 10,000 daltons) was found to stimulate the delayed hypersensitivity reaction in guinea-pigs injected with BCG. It was also found to reduce the hemagglutination titre in mice injected with the APR 8 influenza virus and to raise the antiflagellar agglutinins titre in rats injected with TH Salmonella vaccine. The cellular type of immune reactions was stronger than the humoral one.

摘要

发现给予含有低分子量(低于10,000道尔顿)胸腺多肽的TP2提取物,可刺激接种卡介苗的豚鼠的迟发型超敏反应。还发现它可降低接种APR 8流感病毒的小鼠的血凝滴度,并提高接种TH沙门氏菌疫苗的大鼠的抗鞭毛凝集素滴度。免疫反应的细胞类型比体液类型更强。

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