Jajić I, Pećina M, Krstulović B, Kovacević D, Pavicić F, Spaventi S
Scand J Rheumatol. 1980;9(2):89-96. doi: 10.3109/03009748009098136.
Nineteen patients with PHO with onset in childhood are presented. In 7 cases the syndrome was found in other family members too. In clinical, X-ray scintigraphic, arteriographic, and plethysmographic investigations, joint affection was found in 14 patients. Clubbing of the fingers and toes was seen in all the patients and a periosteal reaction was found in the long bones in 11 patients. Arteriography was carried out in 5 patients and showed hypervascularization and arteriovenous anastomoses in the clubbed fingers. The gas analysis of the arterial blood did not show any pathological changes. The histological finding showed poorly vascularized and oedematous periarticular tissue and ossification in the periosteal area, while in the synovial membrane, slight, nonspecific inflammatory changes were seen.
本文报告了19例儿童期发病的厚皮性骨膜病患者。其中7例患者的家族其他成员也患有该综合征。临床、X线闪烁扫描、动脉造影和体积描记法检查发现，14例患者有关节受累。所有患者均有手指和足趾杵状指，11例患者长骨有骨膜反应。对5例患者进行了动脉造影，结果显示杵状指有血管增多和动静脉吻合。动脉血气分析未显示任何病理变化。组织学检查发现，关节周围组织血管化不良且水肿，骨膜区域有骨化，而滑膜有轻微的非特异性炎症改变。
