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良性食管疾病左胸开胸术后的低氧血症

Hypoxaemia after left thoracotomy for benign oesophageal disease.

作者信息

Bainbridge E T, Matthews H R

出版信息

Thorax. 1980 Apr;35(4):264-8. doi: 10.1136/thx.35.4.264.

Abstract

Arterial blood gases were measured before and after operation in 14 patients undergoing conservative oesophageal surgery via a left thoracotomy. All the patients had a preoperative partial pressure of oxygen (PO2) of greater than 10 kPa, and none gave a history of chronic respiratory disease. All exhibited a fall in PO2 values after operation, the mean maximum reduction being 31%. The overall pattern of hhypoxaemia was similar to that previously reported after pulmonary resection, and upper abdominal surgery, characterised by the greatest reduction in PO2 on the first two postoperative days, followed by a gradual return towards preoperative values. In addition, there was a marked similarity in the degree of hypoxaemia observed by Parfey et al and by ourselves. These findings are attributed to similar changes occurring in pulmonary function in both series of patients, caused at least in part by different factors associated specifically with the two surgical approaches involved. In our experience, left thoracotomy, even without pulmonary resection, is associated with significant postoperative hypoxaemia. Knowledge of this may assist in the selection of patients for surgery and in their subsequent management.

摘要

对14例经左胸切口行保守性食管手术的患者在手术前后测定了动脉血气。所有患者术前氧分压(PO2)均大于10 kPa,且均无慢性呼吸系统疾病史。所有患者术后PO2值均下降,平均最大降幅为31%。低氧血症的总体模式与先前报道的肺切除术后及上腹部手术后相似,其特征为术后头两天PO2下降幅度最大,随后逐渐恢复至术前水平。此外,Parfey等人和我们观察到的低氧血症程度有明显相似之处。这些发现归因于两组患者肺功能发生的相似变化,至少部分是由与所涉及的两种手术方式相关的不同因素引起的。根据我们的经验,即使不进行肺切除,左胸切口手术也会导致明显的术后低氧血症。了解这一点可能有助于手术患者的选择及其后续管理。

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本文引用的文献

1
HYPOXAEMIA AFTER PARTIAL GASTRECTOMY.胃部分切除术后的低氧血症
Thorax. 1965 Jan;20(1):73-5. doi: 10.1136/thx.20.1.73.
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Hypoxaemia after general anaesthesia.全身麻醉后的低氧血症。
Lancet. 1962 Sep 29;2(7257):631-2. doi: 10.1016/s0140-6736(62)92541-2.
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Mechanisms of postoperative hypoxaemia.术后低氧血症的机制。
Proc R Soc Med. 1972 Jan;65(1):12-4. doi: 10.1177/003591577206500105.
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Postoperative changes in gas tensions of arterial blood and in ventilatory function.
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Postoperative hypoxaemia and oxygen therapy.
Br J Surg. 1977 Jun;64(6):390-3. doi: 10.1002/bjs.1800640604.

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