Gmelin E, von Lieven H
Strahlentherapie. 1980 Sep;156(9):611-5.
Fourteen patients are reported, 10 males and 4 females, who have been irradiated for eosinophilic granuloma of bone (8 of them for recurrences). Seven were aged between 1 and 30 years, seven were over 30 years old. In half of the patients, focal lesions from eosinophilic granuloma were localized in the region of the visceral and cerebral crane. Ratio of solitary eosinophilic granuloma to multifocal eosinophilic granuloma was 2.5 : 1. Of the 14 patients, 11 obtained remission (follow-up: 7 months until 17 years) after a dose generally amounting to 2000 or 3000 rad (20 to 30 Gy). In 3 patients aged between 30 and 57 years recurrences appeared following irradiation. None of the patients, however, died of his disease till now. The prognosis is good. If surgery or cytostatic therapy have been failing, cure of the disease is still possible with irradiation.
报告了14例患者,其中男性10例,女性4例,均因骨嗜酸性肉芽肿接受了放射治疗(其中8例为复发病例)。7例年龄在1至30岁之间,7例年龄超过30岁。一半患者的嗜酸性肉芽肿局灶性病变位于内脏和脑颅区域。孤立性嗜酸性肉芽肿与多灶性嗜酸性肉芽肿的比例为2.5:1。14例患者中,11例在接受一般剂量为2000或3000拉德(20至30戈瑞)的放疗后获得缓解(随访时间为7个月至17年)。3例年龄在30至57岁之间的患者在放疗后出现复发。然而,目前尚无患者死于该疾病。预后良好。如果手术或细胞抑制疗法失败,放疗仍有可能治愈该疾病。