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[放射治疗在脊髓内胶质瘤治疗中的应用(作者译)]

[Radiation therapy in the treatment of intraspinal gliomas (author's transl)].

作者信息

Glanzmann C

出版信息

Strahlentherapie. 1980 Sep;156(9):616-20.

PMID:7434394
Abstract

Between 1943 and 1977, 23 patients with intraspinal primary tumors received radiotherapy in our clinic, 4 of 7 patients with ependymoma are alive. Of 10 patients with astrocytoma or oligodendroglioma, 4 are dead with tumor, 2 are alive with signs of progressive disease, 3 are alive without disease and 1 patient was lost from follow-up. Of 7 patients with other tumors - in some cases without histologic verification - only 2 are alive without disease. Radical resection of intraspinal gliomas is the tratment of choice, and radiotherapy is reserved for inoperable or subtotally resected tumors. The recommended tumor dose is 4500 to 5500 rd with the usual fractionation, depending on the localization and field length. The survival rates after 10 years and more are about 40% in patients with astrocytoma, 605 in patients with ependymomas of the cord proper and more than 905 in patients with ependymomas of the cauda equina.

摘要

1943年至1977年间,我院有23例脊髓原发性肿瘤患者接受了放射治疗,7例室管膜瘤患者中有4例存活。10例星形细胞瘤或少突胶质细胞瘤患者中,4例死于肿瘤,2例存活但有疾病进展迹象,3例存活且无疾病,1例失访。7例其他肿瘤患者(部分病例未经组织学证实)中,只有2例存活且无疾病。脊髓胶质瘤的根治性切除是首选治疗方法,放射治疗适用于无法手术或次全切除的肿瘤。根据肿瘤的位置和照射野长度,推荐的肿瘤剂量为4500至5500拉德,采用常规分割方式。星形细胞瘤患者10年及以上的生存率约为40%,脊髓室管膜瘤患者为60%,马尾室管膜瘤患者超过90%。

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