Eliseev V V, Pliss G B, Chernina L A
Vopr Onkol. 1980;26(10):75-9.
During histochemical studies of sarcomas, induced in rats by skin implants of ethacryl plastic, fuchsinophil and argyrophil fibres were found as well as the deposits of chondroitin-4-and chondroitin-6-sulfate in the intercellular space of tumors. Electron microscopy enabled determination of collagen fibrilles and collagen fibre bundles even in low-differentiated neoplasms. Based on the histochemical and ultrastructural features in all these disc-induced tumors are referred to as fibrosarcomas.
在用甲基丙烯酸塑料皮肤植入物诱导大鼠产生肉瘤的组织化学研究过程中,发现了嗜品红纤维和嗜银纤维,以及肿瘤细胞间空间中硫酸软骨素-4和硫酸软骨素-6的沉积。电子显微镜检查甚至能够在低分化肿瘤中确定胶原原纤维和胶原纤维束。基于所有这些椎间盘诱导肿瘤的组织化学和超微结构特征,它们都被归类为纤维肉瘤。