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[人类大脑半球的神经化学不对称性]

[Neurochemical asymmetry of human cerebral hemispheres].

作者信息

Kononenko V S

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1980 Jul-Aug;30(4):773-9.

PMID:7434951
Abstract

The study was concerned with cholinesterase activity and acetylcholine content in the cortical tissue of the human brain, obtained in autopsy and during neurosurgery. A symmetry of cholinesterase activity was found in paired cortical zones of the cutaneous analyser, while in the cortical substance of the motor analyser, its activity was asymmetrical. In the parietal cortex the acetylcholine content was almost equal on two sides; a tendency to its asymmetry was noted in the frontal area. These characteristics of interhemispheric transmitter-enzyme relations between symmetrical cortical centres seem to be a link in the mechanism underlying paired and asymmetrical activity of cortical areas of the cerebral hemispheres in humans.

摘要

该研究关注的是在尸检和神经外科手术过程中获取的人类大脑皮质组织中的胆碱酯酶活性和乙酰胆碱含量。在皮肤分析器的成对皮质区域中发现了胆碱酯酶活性的对称性,而在运动分析器的皮质物质中,其活性是不对称的。在顶叶皮质中,两侧的乙酰胆碱含量几乎相等;在额叶区域则注意到有不对称的趋势。对称皮质中心之间半球间递质 - 酶关系的这些特征似乎是人类大脑半球皮质区域成对和不对称活动潜在机制中的一个环节。

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