Ahnve S, Helmers C, Lundman T
Acta Med Scand. 1980;208(1-2):55-60. doi: 10.1111/j.0954-6820.1980.tb01150.x.
QTc intervals were measured retrospectively in 46.3 survivors of AMI with a mean age of 65 years. The measurement was made one at discharge from hospital. Patients with anterior infarcts had significantly longer QTc intervals than those with inferior or uncertain infact localization. A weak but significant correlation was found between S-GOT maximum and QTc interval. Patients with ventricular arrhythmias in the CCU had longer QTc intervals. Patients with a poor long-term prognosis had significantly shorter QTc intervals. This finding was explained by digitalis therapy. Among patients without bundle branch block, digitalis and quinidine, those below 66 years of age who died within the first six months tended to have longer QTc intervals than the survivors. It is concluded that measurements of QTc interval at discharge have no long-term predictive value. This factor may, however, have some bearing on the short-term prognosis in younger patients without therapy which affects the QTc interval.
对46例平均年龄65岁的急性心肌梗死（AMI）幸存者进行了QTc间期的回顾性测量。测量在出院时进行。前壁梗死患者的QTc间期明显长于下壁梗死或梗死部位不确定的患者。血清谷草转氨酶（S-GOT）最高值与QTc间期之间存在微弱但显著的相关性。冠心病监护病房（CCU）中发生室性心律失常的患者QTc间期较长。长期预后较差的患者QTc间期明显较短。这一发现可用洋地黄治疗来解释。在无束支传导阻滞、未使用洋地黄和奎尼丁的患者中，66岁以下在头6个月内死亡的患者QTc间期往往比幸存者更长。得出的结论是，出院时QTc间期的测量没有长期预测价值。然而，这一因素可能对未接受影响QTc间期治疗的年轻患者的短期预后有一定影响。
