Stern L, Firth B G, Dehmer G J, Johnson S M, Markham R V, Lewis S E, Hillis L D
Am J Cardiol. 1980 Nov;46(5):827-31. doi: 10.1016/0002-9149(80)90435-x.
This study was performed to assess the influence of selective coronary arteriography on left ventricular volumes and ejection fraction in man. In 30 patients with assorted cardiac diseases, left ventricular end-diastolic and end-systolic volumes and ejection fraction were quantitated immediately before and after selective coronary arteriography. In 19 patients (Group A), contrast left ventriculography was performed immediately before and after selective coronary arteriography. In the remaining 11 patients (Group B), multigated equilibrium blood pool imaging was performed just before and after coronary arteriography. In both groups, mean systemic arterial pressure and heart rate did not change from just before the first to immediately before the second assessment of left ventricular volumes and ejection fraction, but left ventricular end-diastolic pressure increased. End-diastolic and end-systolic volume indexes, and ejection fraction did not change from just before to immediately after selective coronary arteriography. Therefore, selective coronary arteriography (1) consistently causes an increase in left ventricular end-diastolic pressure but (2) exerts no effect on left ventricular volumes and ejection fraction, even in patients with severely compromised left ventricular function.
本研究旨在评估选择性冠状动脉造影对人体左心室容积和射血分数的影响。对30例患有各种心脏病的患者，在选择性冠状动脉造影前后即刻对左心室舒张末期和收缩末期容积以及射血分数进行定量分析。19例患者（A组）在选择性冠状动脉造影前后即刻进行了对比剂左心室造影。其余11例患者（B组）在冠状动脉造影前后进行了多门控平衡血池显像。两组中，从首次评估左心室容积和射血分数前到第二次评估前即刻，平均体动脉压和心率均未改变，但左心室舒张末期压力升高。舒张末期和收缩末期容积指数以及射血分数在选择性冠状动脉造影前后即刻未发生变化。因此，选择性冠状动脉造影（1）持续导致左心室舒张末期压力升高，但（2）即使对左心室功能严重受损的患者，也不会对左心室容积和射血分数产生影响。
