Rawlings C A
Can J Comp Med. 1978 Oct;42(4):452-9.
Heartworm diseases in dogs is an infectious disease that produces pulmonary hypertension. Dogs with the early vascular changes of heartworm disease, but without the clinical cardiopulmonary signs and pulmonary hypertension, were studied. Dogs with early heartworm were identified that had an exaggerated hypertensive response to hypoxia and to postaglandin F2alpha as compared to those of normal dogs. The pulmonary hypertensive response of dogs with spontaneous heartworm disease varied widely between individuals.
犬心丝虫病是一种会导致肺动脉高压的传染病。对患有心丝虫病早期血管变化但无临床心肺体征和肺动脉高压的犬进行了研究。研究发现,与正常犬相比,患有早期心丝虫病的犬对低氧和前列腺素F2α的高血压反应更为强烈。自发性心丝虫病犬的肺动脉高压反应在个体之间差异很大。