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采用放射免疫分析法(RIA,Z凝胶法)测定了结肠直肠癌和息肉患者血浆中的癌胚抗原(CEA)浓度。

[The CEA-concentration in plasma of patients with colorectal carcinoma and polyps has been determined by radioimmunoassay (RIA, Z-gel-method)].

作者信息

Ziegenbein R, Jacobasch K H, Pilgrim G, Seifart W

出版信息

Arch Geschwulstforsch. 1980;50(2):165-8.

PMID:7436700
Abstract

82% of the cancer patients and 52% of the patients with polyps showed CEA levels above the upper normal limit of 2,5 microgram/1. CEA-values of more than 10 microgram/1 could only be detected in patients with carcinoma. Complete removal of the tumour by surgery has been followed by a marked decrease of prior increased plasma-CEA to values in the normal range, which could not be observed in the cases with tumour residues or metastases. In the patient's follow-up recurrence or metastases could be recognized several months before clinical detection by a renewed increased of the CEA-level in plasma.

摘要

82%的癌症患者和52%的息肉患者癌胚抗原(CEA)水平高于2.5微克/升的正常上限。仅在癌症患者中检测到癌胚抗原值超过10微克/升。手术完全切除肿瘤后,先前升高的血浆癌胚抗原显著下降至正常范围,而在有肿瘤残留或转移的病例中未观察到这种情况。在患者随访过程中,血浆癌胚抗原水平再次升高可在临床检测前数月识别复发或转移。

相似文献

1
[The CEA-concentration in plasma of patients with colorectal carcinoma and polyps has been determined by radioimmunoassay (RIA, Z-gel-method)].采用放射免疫分析法(RIA,Z凝胶法)测定了结肠直肠癌和息肉患者血浆中的癌胚抗原(CEA)浓度。
Arch Geschwulstforsch. 1980;50(2):165-8.
2
[Value of radioimmunological serum levels of carcinoembryonic antigen in the postoperative monitoring of rectocolonic cancer].[癌胚抗原放射免疫血清水平在结直肠癌术后监测中的价值]
Ann Gastroenterol Hepatol (Paris). 1984 Jul-Sep;20(4):203-6.
3
[Carcinoembryonic antigen in cancer of the rectum and colon].
Klin Med (Mosk). 1983 Jul;61(7):86-9.
4
Correlation of single and serial CEA determinations with the clinical evolution of cancer patients.
Arch Geschwulstforsch. 1982;52(2):105-12.
5
Clinical significance of carcinoembryonic antigen (CEA) in patients with adenocarcinoma in colon and rectum.癌胚抗原(CEA)在结肠直肠癌患者中的临床意义。
Acta Chir Scand. 1982;148(2):189-93.
6
[Does an obturation in colorectal cancer also modify the behavior of the serum CEA level?].[结直肠癌中的充填术是否也会改变血清癌胚抗原水平的变化规律?]
Zentralbl Chir. 1983;108(15):967-73.
7
Serum CA 242 and CEA detect different patients with recurrent colorectal cancer.血清CA 242和癌胚抗原可检测出不同的复发性结直肠癌患者。
Anticancer Res. 1996 Mar-Apr;16(2):981-6.
8
[Leukocyte migration test and determination of carcinoembryonic antigens in the postoperative follow-up care of colon and rectum carcinoma].[白细胞迁移试验及癌胚抗原测定在结肠直肠癌术后随访中的应用]
Chir Forum Exp Klin Forsch. 1978(1978):221-5.
9
[Value and limits of the determination of carcinoembryonic antigen (CEA) in postoperative evaluation of patients with colonic and rectal carcinomas].[癌胚抗原(CEA)测定在结直肠癌患者术后评估中的价值与局限性]
Schweiz Med Wochenschr. 1975 Nov 15;105(46):1533-8.
10
[Carcinoembryonic antigen: diagnosis and tumor progression in gastrointestinal tumors].[癌胚抗原:胃肠道肿瘤的诊断与肿瘤进展]
Dtsch Med Wochenschr. 1985 Dec 20;110(51-52):1963-8. doi: 10.1055/s-2008-1069121.

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1
Blood CEA levels for detecting recurrent colorectal cancer.用于检测复发性结直肠癌的血液癌胚抗原水平。
Cochrane Database Syst Rev. 2015 Dec 10;2015(12):CD011134. doi: 10.1002/14651858.CD011134.pub2.