Locke K B, McEwan D R, Hamdorf I J
Aust Vet J. 1980 Aug;56(8):379-83. doi: 10.1111/j.1751-0813.1980.tb09563.x.
Horses and cattle fed swainsona (Swainsona canescens var horniana) over a period of 8 to 10 weeks lost condition and became incoordinated and hypersensitive. Histological examination of tissues from affected animals revealed the characteristic changes of widespread cellular vacuolation and axonal spheroids in the CNS. Cattle withdrawn from the toxic plant after being fed for varying periods up to 8 weeks returned to normal. Serum alpha-mannosidase activity declined significantly in cattle during the test period, whereas in horses that activity rose. Serum alkaline phosphatase levels increased significantly in cattle but not in horses. The similarity of the clinical signs of disease in horses was noted to those seen in Indigofera linnaei poisoning (Birdsville disease). Differential diagnosis can be made by botanical observations and by an increased frequency of vacuolated lymphocytes in the blood in swainsona poisoning.
马和牛连续8至10周食用灰叶豆（Swainsona canescens var horniana）后，体重下降，出现共济失调和过敏反应。对患病动物组织进行组织学检查发现，中枢神经系统出现广泛细胞空泡化和轴突球体的特征性变化。在喂食长达8周的不同时间段后，将牛从有毒植物中撤出，它们恢复了正常。在试验期间，牛的血清α-甘露糖苷酶活性显著下降，而马的该活性则上升。牛的血清碱性磷酸酶水平显著升高，而马则没有。人们注意到马的疾病临床症状与林氏木蓝中毒（伯兹维尔病）的症状相似。可通过植物观察以及灰叶豆中毒时血液中空泡化淋巴细胞频率增加来进行鉴别诊断。
