Stewart J, Kay A B
Clin Exp Immunol. 1980 May;40(2):423-6.
Histamine, at high concentrations, enhanced the uptake of isotopic histidine by guinea-pig basophils. The effect was partially reversed by H1-, but not H2-, histamine receptor antagonists. These data suggest that histamine has a bioregulatory role in its own synthesis.
高浓度的组胺可增强豚鼠嗜碱性粒细胞对同位素组氨酸的摄取。H1组胺受体拮抗剂可部分逆转该效应,而H2组胺受体拮抗剂则不能。这些数据表明,组胺在其自身合成过程中具有生物调节作用。