Richmond I L, Wilson C B
Childs Brain. 1980;7(2):85-94.
Despite the predominance of histologically benign tumors in the parasellar region of children, their proximity to the hypothalamus, optic nerves and tracts, and the internal carotid artery and its branches often renders surgical removal exceptionally difficult. The possible presence of a variety of tumor types makes biopsy verification of tumor diagnosis essential. The surgical management, radiotherapeutic treatment, and clinical follow-up of a group of 74 children whose preoperative findings were reviewed in the preceding paper are presented to illustrate the management of four major tumor types encountered: craniopharyngioma, pituitary adenoma, germinoma, and diencephalic glioma. Both subfrontal and transsphenoidal surgical approaches were used. Although total resection of benign tumors is desirable, prudent use of a variety of techniques can achieve effective neurosurgical management and optimal long-term results.
尽管组织学上良性肿瘤在儿童鞍旁区域占主导地位，但它们与下丘脑、视神经及视束、颈内动脉及其分支相邻，这常常使得手术切除异常困难。多种肿瘤类型的可能存在使得通过活检来核实肿瘤诊断至关重要。本文介绍了一组74例儿童的手术治疗、放射治疗及临床随访情况，其术前检查结果已在前一篇论文中进行了回顾，以说明所遇到的四种主要肿瘤类型的治疗方法：颅咽管瘤、垂体腺瘤、生殖细胞瘤和间脑胶质瘤。采用了额下入路和经蝶入路两种手术方式。虽然理想的情况是完全切除良性肿瘤，但谨慎运用多种技术能够实现有效的神经外科治疗并取得最佳的长期效果。
