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眼电图与脉络膜恶性黑色素瘤

The EOG and choroidal malignant melanomas.

作者信息

Staman J A, Fitzgerald C R, Dawson W W, Barris M C, Hood C I

出版信息

Doc Ophthalmol. 1980 Oct 15;49(2):201-9. doi: 10.1007/BF01886618.

DOI:10.1007/BF01886618
PMID:7438982
Abstract

Fifty-four patients with a unilateral pigmented choroidal lesion were studied with electrooculography (EOG). Eighteen of 21 patients with histologically proven (13) or presumed (8) malignant tumors of the choroid had light peak-dark trough ratios (L/D) less than or equal to 150. Seventeen of 21 patients in the malignant group had an interocular L/D difference (L/Dd) greater than or equal to 23%, whereas only one of 33 patients with nevi or a condition simulating a nevus had a percent difference of such magnitude. Combining the L/D and L/Dd criteria resulted in a 98% accurate double-blind prediction of the final clinical/pathological results. The EOG is an objective, noninvasive test useful in the diagnosis of choroidal malignant melanomas.

摘要

对54例单侧色素性脉络膜病变患者进行了眼电图(EOG)检查。在21例经组织学证实(13例)或疑似(8例)脉络膜恶性肿瘤的患者中,有18例的光峰-暗谷比值(L/D)小于或等于150。恶性组21例患者中有17例的两眼间L/D差值(L/Dd)大于或等于23%,而在33例患有痣或疑似痣的患者中,只有1例的差值达到如此程度。将L/D和L/Dd标准相结合,对最终临床/病理结果的双盲预测准确率达98%。眼电图是一种客观、无创的检查方法,对脉络膜恶性黑色素瘤的诊断很有用。

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