Steffen H, Van der Loos H
Exp Brain Res. 1980;40(4):419-31. doi: 10.1007/BF00236150.
There is a statistically significant order in the tangential orientation of stellate cell dendrites, both spiny and smooth, in layer IV of the barrelfield of the mouse parietal cortex. Neurones situated in a barrel side have most of their dendrites oriented towards the barrel hollow; those situated in the hollow preferentially orient their dendrites parallel to the long axis of the barrel. A quantitative measure of the orientation of individual dendrites in barrelfields of 60-day old mice was obtained using a semi-automatic computer-microscope and a minicomputer. In the same manner, the dendrite orientation of layer IV stellate cells was determined in barrelfields, whose (cytoarchitectonic) pattern had been experimentally altered through lesions of the middle row of the mystacial vibrissal follicles at birth. The dendrites of these cells are oriented in harmony with the novel parcellation of the cortex. Consequently, for cells in the altered areas of the barrelfields, the dendrite orientation is different from that of cells with identical positions in a normal field (see Fig. 8). We tentatively interpret these findings as an adaptation of dendrite orientation to an altered pattern of thalamic input to layer IV that, in turn, is a consequence of the peripheral manipulation.
在小鼠顶叶皮质桶状区IV层中，棘状和光滑的星状细胞树突的切线方向存在统计学上显著的顺序。位于桶壁一侧的神经元，其大部分树突朝向桶腔；位于桶腔内的神经元则优先将其树突沿桶的长轴平行排列。使用半自动计算机显微镜和小型计算机，对60日龄小鼠桶状区单个树突的方向进行了定量测量。同样地，通过出生时损伤触须毛囊中间排，实验性改变了（细胞构筑）模式的桶状区中，确定了IV层星状细胞的树突方向。这些细胞的树突方向与皮质的新分区协调一致。因此，对于桶状区改变区域中的细胞，其树突方向与正常区域中相同位置的细胞不同（见图8）。我们初步将这些发现解释为树突方向对IV层丘脑输入改变模式的一种适应，而这种改变又是外周操作的结果。
