围产期暴露于乙醇的大鼠大脑中的突触发育。
Synaptic development in brains of rats exposed perinatally to ethanol.
作者信息
Slotkin T A, Schanberg S M, Kuhn C M
出版信息
Experientia. 1980 Aug 15;36(8):1005-7. doi: 10.1007/BF01953850.
PMID:7439320
Abstract
Development of brain synaptosomal uptakes of 3H-norepinephrine and 3H-dopamine in pups whose mothers received ethanol were nearly normal. However, development of synaptosomal uptake of 3H-serotonin was significantly lower than in controls, while uptake of 3H-norepinephrine into synaptic storage vesicles was increased.
摘要
母亲摄入乙醇的幼崽大脑中3H-去甲肾上腺素和3H-多巴胺的突触体摄取发育情况基本正常。然而，3H-5-羟色胺的突触体摄取发育显著低于对照组，而3H-去甲肾上腺素进入突触储存囊泡的摄取则增加。
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