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[精神兴奋剂作用下大脑皮质视觉区兴奋变化的特征]

[Characteristics of the excitation changes in the visual area of the cerebral cortex under psychostimulant action].

作者信息

Machula A I, Barkov N K, Pokryshkin V I

出版信息

Farmakol Toksikol. 1980 Jul-Aug;43(4):338-41.

PMID:7439362
Abstract

The experiments were carried out on cats with chronically implanted electrodes. It was shown by means of recording the primary responses (PR) of the visual cortex that amphetamine (0,5 mg/kg), sydnocarb (3 mg/kg), and catinon (1 mg/kg) depress the amplitude of the single PR and lessen concurrently the depression of the testing response in the cycle of PR recovery. Cocaine (1 mg/kg) suppresses the amplitude of the single PR and intensifies the depression of the testing PR in the recovery cycle.

摘要

实验是在长期植入电极的猫身上进行的。通过记录视觉皮层的初级反应(PR)表明,苯丙胺(0.5毫克/千克)、西诺卡(3毫克/千克)和卡替诺(1毫克/千克)会降低单个PR的幅度,并同时减轻PR恢复周期中测试反应的抑制。可卡因(1毫克/千克)会抑制单个PR的幅度,并加剧恢复周期中测试PR的抑制。

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